Charles-Édouard Brown-Séquard,FRS (Port Louis, 8 April 1817 – Sceaux, 2 April 1894) was a Mauritian physiologist and neurologist. He studied medicine in Paris, and later worked in the US (University of Virginia, Harvard), London (National Hospital for the Paralysed and Epileptic, later known as the National Hospital for Neurology and Neurosurgery) and Paris (he succeed Claude Bernard in 1878 as professor of experimental medicine in the Collège de France).
He was the first scientist to work out the physiology of the spinal cord, demonstrating that the decussation of the fibres carrying pain and temperature sensation occurs in the cord itself. His name was immortalized in the history of medicine with the description of a syndrome which bears his name (Brown-Séquard syndrome) due to the hemisection of the spinal cord, which he described after observing accidental injury of the spinal cord in farmers cutting sugar cane in Mauritius.
- Brown-Séquard’s biography
- Charles-Édouard Brown-Séquard [Encyclopaedia Britannica]
- Brown-Séquard’s description of spontaneous cerebellar haemorrhage [Journal of Neurology, Neurosurgery, and Psychiatry]
- Brown-Séquard syndrome [Whonamedit]
- Brown-Séquard syndrome [NIH National Institute of Neurological Disorders and Stroke]
- The National Hospital for Neurology and Neurosurgery, Queen Square [UCL Hospitals]