1883. Congo Red staining

This staining method was discovered by Paul Böttiger in 1883, who was working from the Fredrich Bayer Company while he was trying to synthesize a pH indicator.

This is a red colorant but the reason why it is named Congo Red is still a mystery.

This stain doesn’t need a mordant to colourize the textile fibre.

In the beginning this dye was used to search traces of acid in animal’s intestinal traces, but the most important utilization in medicine was discovered by Belgian neuropathologist: he noted that it can be used to diagnose amyloidosis.

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